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Developing an Ethical Evaluation Framework for Coercive Antimicrobial Stewardship Policies

机译:为强制性抗菌药物管理政策制定道德评估框架

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摘要

Antimicrobial resistance (AMR) has been declared one of the top ten global public health threats facing humanity. To address AMR, coercive antimicrobial stewardship policies are being enacted in some settings. These policies, like all in public health, require ethical justification. Here, I introduce a framework for ethically evaluating coercive antimicrobial stewardship policies on the basis of ethical justifications (and their limitations). I consider arguments from effectiveness; duty of easy rescue; tragedy of the commons; responsibility-tracking; the harm principle; paternalism; justice and development; a precautionary approach; and professional duties. I consider how these justifications might form the basis for developing a comprehensive ethical framework, and the need for this to be context-specific and aligned with the priorities, evidence and needs of the particular jurisdictions in which a policy is to be enacted. I demonstrate how the ethical justifications might be used by reference to an example policy of the EU ban on the use of certain human-critical antibiotics for livestock, before concluding with challenges for further development of the framework.
机译:抗微生物药物耐药性 (AMR) 已被宣布为人类面临的十大全球公共卫生威胁之一。为了应对抗微生物药物耐药性问题,一些地区正在制定强制性的抗微生物药物管理政策。这些政策,就像公共卫生领域的所有政策一样,需要道德理由。在这里,我介绍了一个框架,用于根据道德理由(及其局限性)对强制性抗菌药物管理政策进行道德评估。我从有效性考虑论点;轻松救援的职责;公地悲剧;责任跟踪;伤害原则;家长式;正义与发展;一种预防性的方法;和专业职责。我考虑了这些理由如何构成制定综合道德框架的基础,以及使其因地制宜并与将要制定政策的特定司法管辖区的优先事项、证据和需求保持一致的必要性。在总结进一步发展该框架的挑战之前,我通过参考欧盟禁止对牲畜使用某些对人类至关重要的抗生素的示例政策来展示如何使用道德理由。

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