Pulmonary hypertension (PH) is a common complication in dogs with degenerative mitral valve disease (DMVD). The aim of this study was to determine the survival time and to determine factors related to the survival time of dogs with PH secondary to DMVD stage C. A retrospective study was conducted in 37 dogs with PH secondary to DMVD stage C to analyse the median survival time and associated factors such as age, sex, breed, body weight, the presence of syncope, heart rate, systolic blood pressure, manifestation of congestive heart failure (CHF), vertebral heart score (VHS), the presence of left or right heart enlargement, probability of PH and medication. Data were analysed using the Log-Rank test and plotted with the Kaplan-Meier curve. The results showed that the median survival time of dogs with PH secondary to DMVD stage C was 368 days, and factors that shortened the median survival time of dogs with PH secondary to DMVD stage C were mixed breeds, VHS > 11.5, the presence of right heart enlargement, ascites and high probability of PH. Factors associated with an increased hazard of death were mixed breed dogs, dogs with right heart enlargement and ascites. These findings may be useful for the prognosis and management of dogs with PH secondary to DMVD stage C.
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机译：肺动脉高压 （PH） 是患有退行性二尖瓣疾病 （DMVD） 的狗的常见并发症。本研究的目的是确定继发于 DMVD C 期的 PH 狗的生存时间并确定与生存时间相关的因素。对 37 只继发于 DMVD C 期的 PH 狗进行了一项回顾性研究，以分析中位生存时间和相关因素，例如年龄、性别、品种、体重、晕厥的存在、心率、收缩压、充血性心力衰竭 （CHF） 的表现、椎心评分 （VHS）、存在左心或右心扩大、 PH 和药物的可能性。使用 Log-Rank 检验分析数据，并用 Kaplan-Meier 曲线绘制。结果显示，继发于 DMVD C 期的 PH 犬的中位生存时间为 368 天，缩短继发于 DMVD C 期的 PH 犬的中位生存时间的因素是混血、VHS > 11.5、存在右心扩大、腹水和 PH 可能性高。与死亡风险增加相关的因素是混种犬， 右心肿大和腹水的狗。这些发现可能有助于继发于 DMVD C 期的 PH 犬的预后和管理。
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