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COVID-19 Pneumonia After SARS-CoV-2 Vaccination with CoronaVac: A Case Series from Turkey

机译:使用 CoronaVac 接种 SARS-CoV-2 疫苗后的 COVID-19 肺炎:来自土耳其的病例系列

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摘要

Coronavirus disease 2019 is a novel viral infection that has caused a pandemic globally. Many kinds of vaccine development studies were conducted to prevent the spread and deaths. The CoronaVac is the most commonly used vaccine in Turkey. Phase 3 trials from various countries revealed that CoronaVac efficacy ranged from 50.7% to 91.25% but increased in moderate or severe cases to 100%. Additionally, it was remarkable owing to high seroconversion rates achieving up to 100%. After the vaccine campaign began in Turkey, critically ill patients continued to admit to our center’s intensive care unit though they had been vaccinated with 2 doses of CoronaVac. The clinical course of these patients revealed that they are still at high risk of severe disease and death. Therefore, we aimed to share these patients’ clinical characteristics and disease course, laboratory, and radiologic data.
机译:2019 冠状病毒病是一种新型病毒感染,已在全球范围内引起大流行。进行了多种疫苗开发研究以防止传播和死亡。CoronaVac 是土耳其最常用的疫苗。来自不同国家的 3 期试验显示,CoronaVac 的有效性在 50.7% 至 91.25% 之间,但在中度或重度病例中提高到 100%。此外,由于血清转化率高达 100%,这一点非常显着。在土耳其开始疫苗接种运动后,危重患者继续入住我们中心的重症监护室,尽管他们已经接种了 2 剂 CoronaVac。这些患者的临床病程表明,他们仍然处于重症和死亡的高风险中。因此,我们旨在分享这些患者的临床特征和病程、实验室和放射学数据。

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