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Evaluation of the efficacy of topical sucralfate on healing haemorrhoidectomy incision wounds and reducing pain severity: A randomised clinical trial

机译:评价局部Sucralfate对愈合出血术切口伤害的疗效降低疼痛严重程度:随机临床试验

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摘要

The healing of haemorrhoidectomy wounds is a main concern of surgeons and patients. Various modalities can improve the quality of wound care after surgery. Antibiotics and topical agents, such as solutions and ointments, have been evaluated. The current research investigates the effects of sucralfate ointment on wound healing (epithelialisation) and postoperative pain after open haemorrhoidectomy. This trial involves two groups of randomly collected patients (n = 40) who underwent open haemorrhoidectomy surgery by the Milligan‐Morgan method. A 10% topical sucralfate ointment was applied to the investigated group's wounds, while the control group patients used Vaseline as a placebo. The present work measured the two outcomes as follows: pain severity by a Visual Analogues Scale (VAS) score and epithelialisation by a surgeon's visual inspection. During the postoperative phase, the mean VAS was 3.70 for the investigated group and 6.90 for the control group. On the average, the completion of epithelialisation for the investigated group was on day 13 as opposed to day 20 for the control group. The topical application of sucralfate ointment on post‐haemorrhoidectomy wound is an effective method for the promotion of healing, also lessens the severity of pain, and reduces the need for analgesics.
机译:痔切除术伤口的愈合是外科医生和患者的主要关注点。各种方式可以提高手术后伤口护理的质量。已经评估了抗生素和局部剂,例如溶液和软膏。目前的研究调查了Sucralfate软膏对伤口愈合(上皮化)和术后疼痛的影响。该试验涉及两组随机收集的患者(n = 40),由千年摩根方法接受开放出血术外切除手术。将10%的局部Sucralfate软膏施用于研究的群体,而对照组患者使用凡士林作为安慰剂。目前的工作测量了两种结果如下:通过外科医生的视觉检查,通过视觉类似物(VAS)评分和上皮疼痛的严重程度。在术后阶段,调查基团的平均VAS为3.70,对照组为6.90。在平均水平,调查组上皮化的完成是在第13天,而不是对照组的第20天。 Sucralfate软膏对后痔切除术伤口的局部应用是促进愈合的有效方法,还减少了疼痛的严重程度,并降低了对镇痛药的需求。

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