CT scans of the maxillary antra in a group of 51 patients with nasopharyngeal carcinoma were compared with those of a control group of 50 patients. Inflammatory thickening of the antral mucosa was demonstrated in 39 of 42 patients with grade WHO (World Health Organization) 2 and 3 nasopharyngeal carcinoma. Biopsy of the antral mucosa in eight of these patients established inflammation and excluded the presence of nasopharyngeal carcinoma in the antrum. In a group of nine patients with WHO 1 tumors, the antral mucosa was normal. Thickening of the antral mucosa was observed in six patients of the control group. The inflammatory thickening of the antral mucosa in the patients with WHO 2 and 3 tumors was obviously more frequent than in the control group. This combination was not found in patients with WHO 1 tumors. The phenomenon cannot be explained by direct extension of nasopharyngeal carcinoma or obstruction of the maxillary osteum. The cause of the mucosal thickening may be immunologic, but remains unclear at this stage. The high frequency of inflammatory thickening of the antral mucosa observed in patients with WHO 2 and 3 tumors should encourage further investigation of causative factors in nasopharyngeal carcinoma.
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机译：与50名患者的对照组的鼻咽癌患者的一组51例患有51名患者的颌骨ANTRA的CT扫描。在42名患者（世界卫生组织）2和3种鼻咽癌中，42例患者的炎症增稠症患者。这些患者中嗜睡粘膜的活组织检查建立了炎症，排除了鼻咽癌的存在。在一组九名患者1名肿瘤的患者中，Antral Mucosa正常。在对照组的6例患者中观察到肛门粘膜的增稠。患者中嗜睡剂粘膜的炎症增厚明显比对照组更频繁。在患者1患者中未发现这种组合。现象不能通过直接延伸鼻咽癌或上颌骨骨膜的阻塞来解释。粘膜增稠的原因可能是免疫学，但在这个阶段仍然不清楚。 WHO 2和3肿瘤患者观察到嗜睡粘膜的高频炎症增厚应鼓励进一步调查鼻咽癌的致病因子。
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