USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription

摘要

a KDM4C protein levels in different cell lines were examined by Western blotting. b Quantification of KDM4C protein levels in (a) (n = 3). c Representative IHC staining pictures for KDM4C in lung adenocarcinoma tissues and adjacent lung tissues. Scale bar, 10 μm. d Statistical analysis of IHC staining to assess KDM4C expression in a lung cancer tissue microarray. e High KDM4C expression is correlated with adverse overall survival in lung cancer patients.