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Outdoor air pollution and the onset and exacerbation of asthma

机译:户外空气污染和哮喘发病和恶化

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摘要

Exposure to outdoor air pollution has been consistently associated with asthma. In this study, we reviewed the epidemiological studies published within the last 5 years on the association between outdoor air pollution and exacerbation and onset of asthma. A large number of studies have been published within the last 5 years. Short-term exposure to outdoor air pollution is associated with exacerbation of pre-existing asthma, manifested as worsening of symptoms and increasing of asthma-related emergency room visits and hospital admissions. Furthermore, increasing evidence suggests that long-term exposure to outdoor air pollution can result in onset of asthma. Children are more susceptible to outdoor air pollution. Future studies should be conducted to explore the mechanisms underlying the association between air pollutants and onset of asthma, including gene involvement. In addition, disentangling the effect of a mixture of air pollutants and identifying the key components of air pollution will complete the existing evidence. More importantly, a better understanding is required on the future impact of air pollution on asthma under a changing climate.
机译:暴露于室外空气污染已经始终如一与哮喘相关。在这项研究中,我们审查了在过去5年内发表的流行病学研究,户外空气污染与加重和哮喘发作之间的关联。在过去5年内发表了大量研究。短期暴露于户外空气污染与预先存在的哮喘的恶化有关,表现为症状恶化和哮喘相关的急诊室访问和医院入学。此外,越来越多的证据表明,长期暴露于室外空气污染可能导致哮喘发作。儿童更容易受到户外空气污染的影响。应进行未来的研究,以探讨空气污染物与哮喘发作之间的关系的机制,包括基因受累。此外,解解空气污染物混合物和鉴定空气污染关键部件的效果将完成现有证据。更重要的是,在不断变化的气候下对空气污染对哮喘的未来影响,需要更好的理解。

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