Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck: A Big and Intriguing Challenge Which May Be Resolved by Integrated Treatments Combining Locoregional and Systemic Therapies

摘要

The purpose of this manuscript is to illustrate the difficulties associated with the treatment of the patient with recurrent metastatic SCCHN. This type of patient is very heterogeneous, including very different cases both as regards the natural history and the types of treatment to be used. The authors then illustrated the possible therapeutic options available and tried to propose the best strategies to be adapted to the individual case, based on the characteristics of the patient and the disease. The main conclusion of the following work is that the multidisciplinary approach is the winning weapon in any patient.