Application of synthetic recombinant multi-epitope antigens and gold nanoparticles for a Pneumocystis pneumonia rapid diagnostic test

摘要

Introduction:Pneumocystis jirovecii pneumonia (PcP) is an important morbidity/mortality factor in immunocompromised patients, whose diagnosis requires respiratory specimens obtained by invasive and costly techniques. Thus, the development of a rapid, cost-effective, minimally invasive and field-friendly test to diagnose PcP would be a significant clinical advance.