Cyclin D1 G870A Polymorphism: Relation to the Risk of ALL Development Prognosis Impact and Methotrexate Cytotoxicity

机译：Cyclin D1 G870A多态性：与所有开发预后的风险预后的影响和甲氨蝶呤细胞毒性有关

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Cyclin D1 (CCND1) regulates cell cycle progression during the late G1 and S phase and takes part in methotrexate metabolism. It was hypothesized that CCND1 gene polymorphism affects acute lymphoblastic leukemia (ALL) development, prognosis and may relate to methotrexate cytotoxicity.

机译：细胞周期蛋白D1（CCND1）在晚期G1和S期间调节细胞周期进展，并参与甲氨蝶呤代谢。假设CCND1基因多态性影响急性淋巴细胞白血病（全部）发育，预后和可涉及甲氨蝶呤细胞毒性。

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期刊名称 Asian Pacific Journal of Cancer Prevention : APJCP
作者
Nadia El Menshawy; Ahmed B El Marghany; Mohamed M Sarhan; Doaa A Aladle;
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作者单位

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年(卷),期 2020(21),10
年度 2020
页码 2941–2947
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

机译：全部;Cyclin D1;CCND1;多态性;甲氨蝶呤;

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专利

1. Cyclin D1 G870A Polymorphism: Relation to the Risk of ALL Development, Prognosis Impact, and Methotrexate Cytotoxicity [J] . Nadia El Menshawy, Ahmed B El Marghany, Mohamed M Sarhan, Asian Pacific Journal of Cancer Prevention . 2020,第10期

机译：Cyclin D1 G870A多态性：与所有开发，预后的风险，预后的影响和甲氨蝶呤细胞毒性有关
2. Polymorphisms of HER2 Ile655Val and cyclin D1 (CCND1) G870A are not associated with breast cancer risk but polymorphic allele of HER2 is associated with nodal metastases. [J] . Naidu R, Yip CH, Taib NA Neoplasma: Journal of Experimental and Clinical Oncology . 2008,第2期

机译：HER2 Ile655Val和细胞周期蛋白D1（CCND1）G870A的多态性与乳腺癌风险无关，但HER2的多态性等位基因与淋巴结转移有关。
3. Influence of CCND1 G870A polymorphism on the risk of HBV-related HCC and cyclin D1 splicing variant expression in Chinese population [J] . Zeng Zhenzhen, Tu Jing, Cheng Jin, Tumour biology : . 2015,第9期

机译：CCND1 G870A基因多态性对中国人群HBV相关HCC和cyclin D1剪接变异体表达风险的影响
4. Single Nucleotide Polymorphisms of CD14 Are Associated with the Development of Respiratory Syncytial Virus Bronchiolitis in Japanese Children [C] . Y. Inoue, N. Shimojo, E.J. Campos, Collegium Internationale Allergologicum . 2007

机译：CD14的单核苷酸多态性与日本儿童呼吸道合胞病毒支气管炎的发育有关
5. Single nucleotide polymorphisms in cancer related genes lead to inter-individual response to prognosis, disease risk and environmental agent metabolism in multiple myeloma and lung cancer. [D] . Haznadar, Majda. 2010

机译：癌症相关基因中的单核苷酸多态性导致对多发性骨髓瘤和肺癌的预后，疾病风险和环境因素代谢的个体间反应。
6. Association between cyclin D1 (CCND1) G870A polymorphism and gastric cancer risk: a meta-analysis [O] . Yafei Zhang, Xianling Zeng, Hongwei Lu, 2016

机译：细胞周期蛋白D1（CCND1）G870A多态性与胃癌风险的关联：一项荟萃分析
7. Influence of CCND1 G870A polymorphism on the risk of HBV-related HCC and cyclin D1 splicing variant expression in Chinese population [O] . Zhenzhen Zeng, Jing Tu, Jin Cheng, 2015

机译：CCND1 G870A基因多态性对中国人群HBV相关HCC和cyclin D1剪接变异体表达风险的影响

Cyclin D1 G870A Polymorphism: Relation to the Risk of ALL Development Prognosis Impact and Methotrexate Cytotoxicity

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