Analysis of the apparent solubility of β-carotene solid dispersion prepared using the hot-melt technology. a β-Carotene solid dispersion consisting of β-carotene, PVP, and one of four emulsifiers was dissolved in phosphate buffer solution (pH 6.8). The two-component formulation of β-carotene and PVP was prepared with a weight ratio of 10%:90% β-carotene: PVP. Values are presented as mean ± SD (n = 3); **P < 0.01 versus PVP only. b β-Carotene solid dispersion consisting of β-carotene, PVP, and Suc in different weight ratios were dissolved in phosphate buffer solution (pH 6.8). The β-carotene solubility was analyzed by HPLC following centrifugation and filtration. Values are presented as mean ± SD (n = 3); **P < 0.01 versus a weight ratio of 10%:90% β-carotene: PVP
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机译:用热熔技术分析β-胡萝卜素固体分散体的表观溶解度。由β-胡萝卜素,PVP和四种乳化剂中的一种组成的β-胡萝卜素固体分散体溶解在磷酸盐缓冲溶液(pH6.8)中。制备β-胡萝卜素和PVP的双组分制剂,重量比为10%:90%β-胡萝卜素:PVP。值显示为平均值±SD(n = 3); ** P <0.01只有PVP。 Bβ-胡萝卜素固体分散体由β-胡萝卜素,PVP和以不同的重量比溶解在磷酸盐缓冲溶液(pH6.8)中。通过离心和过滤后通过HPLC分析β-胡萝卜素溶解度。值显示为平均值±SD(n = 3); ** P <0.01与重量比为10%:90%β-胡萝卜素:PVP
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