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139 Bioavailability of valine in a fermentation biomass product relative to the bioavailability in crystalline L-valine when fed to weanling pigs

机译:139在发酵生物质产品中缬氨酸的生物利用度相对于结晶L-缬氨酸中的生物利用度进料到断奶猪时

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摘要

An experiment was conducted to test the hypothesis that Val from a Val-containing fermentation biomass product (Val-FB; 64.4% L-Val) has a bioavailability of 100% relative to L-Val (98% Val) when fed to weanling pigs. A Val-deficient basal diet containing 0.63% standardized ileal digestible (SID) Val was formulated. Six additional diets were prepared by supplementing the basal diet with 0.08, 0.16, or 0.24% L-Val or 0.12, 0.25, or 0.37% Val-FB to create experimental diets containing 0.71, 0.79, or 0.87% SID Val. A total of 224 weanling pigs (6.87 ± 0.64 kg) were allotted to a randomized complete block design with 7 diets and 8 replicate pens per diet. Diets were fed for 21 d and growth performance was measured on a pen basis. Orthogonal-polynomial contrasts were used to determine linear and quadratic effects of L-Val and Val-FB levels on performance and the effect of Val sources. A linear regression model based on performance was used to estimate the relative bioavailability (RBV) of Val in Val-FB relative to L-Val. The final body-weight (BW) and average-daily-gain (ADG) were greater (P < 0.01) for pigs fed diets supplemented with Val-FB than pigs fed diets supplemented with L-Val (Table 1). The average-daily-feed-intake (ADFI) decreased linearly (P < 0.01), whereas gain-to-feed ratio (G:F) increased (P < 0.01) by supplementing graded levels of both Val sources to the diets. The RBV of Val in Val-FB as determined by ADG, G:F, and final BW was 146, 135, and 143%, respectively, with 95% confidence intervals of 99 to 191%, 83 to 187%, and 70 to 217%, respectively. In conclusion, the linear regression estimated a RBV of at least 100% for Val-FB relative to L-Val, and pigs fed diets supplemented with Val-FB had greater ADG and final BW than pigs fed diets supplemented with the same amount of L-Val.
机译:进行实验以测试含Val的发酵生物质产物(VAL-FB; 64.4%L-VAL)的假设,当喂食到断奶猪时,相对于L-Val(98%Val)的生物利用度为100% 。配制含有0.63%标准化髂骨可消化(SID)VAL的VAL缺陷的基础饮食。通过补充0.08,0.16或0.24%L-VAR或0.12,0.25或0.37%VAL-FB的基础饮食来制备六种额外的饮食,以产生含有0.71,0.79或0.87%SID VAL的实验饮食。共分配了224只断奶猪(6.87±0.64千克),分配给随机的完整块设计,每次饮食7饮食和8个复制钢笔。饮食喂食21天,并在笔的基础上测量生长性能。正交 - 多项式对比度用于确定L-VAL和VAL-FB水平对性能和VAL源的影响的线性和二次效应。基于性能的线性回归模型用于估计相对于L-VAL的VAL中VAL的相对生物利用度(RBV)。对于补充有Val-FB的饲料的猪,最终的体重(BW)和平均日益增长(ADG)更大(P <0.01)比饲料喂养饲料补充有L-VAL的饮食(表1)。平均日饲料进料(ADFI)线性降低(P <0.01),而进料比(G:F)通过补充VAL来源的分级水平对饮食增加(P <0.01)。通过ADG,G:F和最终BW测定的Val-Fb中的VAR的RBV分别为146,135和143%,95%的置信区间为99至191%,83%至187%,70%至70%分别为217%。总之,线性回归估计相对于L-VAL的VAL-FB的RBV至少100%,而补充有VAL-FB的猪的猪具有比饲喂相同数量的猪的饲料更大的ADG和最终BW。 -Val。

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