Fabrication of chitosan-polyvinyl alcohol and silk electrospun fiber seeded with differentiated keratinocyte for skin tissue regeneration in animal wound model

摘要

Schematic representation showed (a) hybrid chitosan (Ch), polyvinyl alcohol (PVA) and silk fiber mat fabrication through electrospinning method and (b) its utilization in full-thickness wound 6 excision rat model to evaluate wound healing potential of transplanted Ch-PVA + Silk fibrous mat pre-seeded MSC-derived keratinocytes