The role of anti-Müllerian hormone (AMH) in ovarian disease and infertility

摘要

The effect of other hormones and proteins on expression of AMH in the ovarian granulosa cells (GC). It has been proven that BMP9 and LH have a positive effect on expression of AMH in GC cells, as well as that estradiol has an adverse effect on the expression of AMH at the stage of antral follicle development. However, the direct effect of androgens on AMH expression is not known. There are conflicting results on effect of FSH on AMH and it is not concluded, whether FSH has a positive or negative effect on AMH expression [8]