Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157

机译：氯吡格雷诱导的大鼠胃损损伤通过稳定的胃五肽BPC 157衰减

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摘要

Although Clopidogrel is safe in healthy volunteers, it can induce recurrence of gastric ulcers in high-risk patients. Here, we investigated the protective effect of the natural product, stable gastric pentadecapeptide 157 (BPC 157) on Clopidogrel-induced gastric injury.

机译：虽然氯吡格雷在健康的志愿者中是安全的，但它可以诱导高风险患者的胃溃疡复发。在这里，我们研究了天然产物，稳定的胃五肽肽157（BPC 157）对氯吡格雷诱导的胃损伤的保护作用。

著录项

期刊名称 Drug Design Development and Therapy
作者
Hailu Wu; Ming Wei; Nan Li; Qin Lu; Sachin Mulmi Shrestha; Jiacheng Tan; Zhenyu Zhang; Guoqiu Wu; Ruihua Shi;
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作者单位

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年(卷),期 2020(-1),-1
年度 2020
页码 -1
总页数 12
原文格式 PDF
正文语种
中图分类药学;药物化学;
关键词

机译：氯吡格雷;BPC 157;血管生成;akt;p38 / mapk;

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专利

1. Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157 [J] . Hailu Wu, Ming Wei, Nan Li, Drug Design, Development and Therapy . 2020,第3期

机译：氯吡格雷诱导的大鼠胃损损伤通过稳定的胃五肽BPC 157衰减
2. Therapy for unhealed gastrocutaneous fistulas in rats as a model for analogous healing of persistent skin wounds and persistent gastric ulcers: stable gastric pentadecapeptide BPC 157, atropine, ranitidine, and omeprazole. [J] . Skorjanec S, Dolovski Z, Kocman I, Digestive Diseases and Sciences . 2009,第1期

机译：大鼠未治愈的胃皮肤瘘的治疗，作为持续性皮肤伤口和持续性胃溃疡类似愈合的模型：稳定的胃五肽BPC 157，阿托品，雷尼替丁和奥美拉唑。
3. Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats. [J] . Jelovac N, Sikiric P, Rucman R, European Journal of Pharmacology: An International Journal . 1999,第1期

机译：五肽五肽BPC 157可减轻精神抑制药引起的干扰：对小鼠和大鼠的僵直和胃溃疡的影响。
4. Effect of Pentadecapeptide BPC 157 on Gastrointestinal Tract [C] . P. Sikiric, S. Seiwerth, R. Rucman, International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection: Focus on GI Tract . 2012

机译：五肽BPC 157对胃肠道胃肠道的影响
5. Roux-en-Y Gastric Bypass Attenuates Obesity-related Liver Injury [D] . Rideout, Drew Alan. 2019

机译：Roux-en-Y胃旁路衰减肥胖相关的肝损伤
6. Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats [O] . Darko Perovic, Danijela Kolenc, Vide Bilic, 2019

机译：稳定的胃五肽BPC 157可以改善脊髓损伤的愈合过程并导致大鼠功能恢复
7. >Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157 [O] . Hailu Wu, Ming Wei, Nan Li, 2020

机译：>氯吡格雷诱导的大鼠的胃损损伤通过稳定的胃五肽BPC 157衰减，BPC 157

Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157

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