Relative abundance of the Prevotella genus within the human gut microbiota of elderly volunteers determines the inter-individual responses to dietary supplementation with wheat bran arabinoxylan-oligosaccharides

摘要

Schematic of the cross-over, randomised, double-blinded design of the human dietary supplementation study, incorporating the addition of Wheat Bran Extract arabinoxylan oligosaccharide (AXOS) and maltodextrin. Control periods, when volunteers were not receiving supplements (5 days each) were included before, in between, and after the supplementation periods (10 days per supplement). Study visits and sample collection days are indicated. Faecal samples were collected at each visit. Blood samples and blood pressure measurements were collected at the start and end of each supplementation period. Food frequency questionnaires were completed at the beginning and end of the study