The PyGNA analysis workflow. a Outline of the GNT and GNA tests. Given an input network, PyGNA maps genes to network nodes, performs GNA and GNT tests, and then outputs the results in CSV format. b Complete workflow. We recognize three main use-cases where PyGNA can be used, including (i) network analysis of high-throughput experiments, (ii) network analysis of curated genesets and iii) simulations of networks and genesets for algorithms benchmarking. PyGNA can perform GNT analysis on single or multiple genesets, along with GNA analysis to identify network associated with other genesets or pathways. Results are provided as CSV files and as high quality PDF figures
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