The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice

摘要

Timeline of the experimental design of this study. Seven- to 8-week-old male C57BL/6 mice were divided into four groups. All mice received G-CSF (200 μg/kg/d) for 5 consecutive days and received subcutaneously a signal AMD3100 (5 mg/kg) 1 h before an intraperitoneal injection of cisplatin 20 mg/kg and injections of 5-bromo-2-deoxyuridine (BrdU) (100 mg/kg/day) for 2 consecutive days from the indicated time