Special Issue Metabolic Engineering and Synthetic Biology Volume 2

摘要

In times of ever-increasing demand for chemicals and the subsequent increase in CO2 in the atmosphere, we have to intensify our efforts to establish a circular (bio) economy. To reduce fossil resource use, renewable carbon sources including biomass and CO2 itself need to be used. The (bio)catalysts of choice that are able to convert these carbon sources into valuable chemicals often have to be tailored to meet the industrial requirements in titer, rate, and yield, and, hence, ultimately, in cost. While exciting examples exist, from vitamins to plastic monomers and bioplastics, the metabolic engineering of such biocatalysts is still time and cost consuming. With the improvement of biological tools and ideas for standardization, creating, and/or building new whole-cell biocatalysts becomes an ever more rapid task.