Extracting single-trial neural interaction using latent dynamical systems model

摘要

Schematics of the behavioral task and examples of neural activities and cross-correlograms. a In a sample epoch, the pole is presented at one location (posterior or anterior) and mice are trained to lick a corresponding port to report pole location in a response epoch, which was signaled by an auditory cue after a 1.3-s delay epoch (upper panel). Examples of spike trains in a single trial (middle panel); the number of spikes in time bins and the rate estimate of neuron N15 (lower panel). b An example of the differences among cross-correlograms (upper panel), spike trains (middle panel), and rate estimates (lower panel). Neural activities of the target neuron (N15) are aligned based on the different reference neurons (N2: black; N7: magenta; N12: cyan)