Detection of Common Deletional of α-Thalassemia 3.7 Kb from Metropolitan Region of Manaus Amazonas Brazil

摘要

Alpha Thalassemia (α-thal) is a heterogeneous group of hereditary alterations caused by deletions that affect alpha regulatory genes, and the 3.7Kb deletion is the most frequent worldwide. The prevalence ranges from 20% and 35% in Brazil, depending mainly on race, predominant in Afro-descendants.