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Development of raster scanning IMRT using a robotic radiosurgery system

机译:使用机器人放射外科系统的光栅扫描IMRT的开发

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摘要

Treatment time with the CyberKnife frameless radiosurgery system is prolonged due to the motion of the robotic arm. We have developed a novel scanning irradiation method to reduce treatment time. We generated treatment plans mimicking eight-field intensity-modulated radiotherapy (IMRT) plans generated for the Novalis radiosurgery system. 2D dose planes were generated with multiple static beam spots collimated by a fixed circular cone. The weights of the uniformly distributed beam spots in each dose plane were optimized using the attraction–repulsion model. The beam spots were converted to the scanning speed to generate the raster scanning plan. To shorten treatment time, we also developed a hybrid scanning method which combines static beams with larger cone sizes and the raster scanning method. Differences between the Novalis and the scanning plan’s dose planes were evaluated with the criterion of a 5% dose difference. The mean passing rates of three cases were > 85% for cone sizes ≤ 12.5 mm. Although the total monitor units (MU) increased for smaller cone sizes in an inverse-square manner, the hybrid scanning method greatly reduced the total MU, while maintaining dose distributions comparable to those with the Novalis plan. The estimated treatment time of the hybrid scanning with a 12.5 mm cone size was on average 22% shorter than that of the sequential plans. This technique will be useful in allowing the CyberKnife with conventional circular cones to achieve excellent dose distribution with a shortened treatment time.
机译:由于机器人臂的运动,延长了Cyber​​ Knife无框架放射外科系统的治疗时间。我们开发了一种新颖的扫描辐照方法,以减少治疗时间。我们生成了为Novalis放射外科系统产生的八场强度调制放射治疗(IMRT)计划的治疗计划。产生2D剂量平面,其中多个静态光束斑点由固定圆形锥体准直。使用吸引排斥模型优化每个剂量平面中均匀分布的光束斑点的重量。光束点被转换为扫描速度以产生光栅扫描计划。为了缩短治疗时间,我们还开发了一种混合扫描方法,该方法将具有较大锥形尺寸和光栅扫描方法的静态梁组合。利用5%剂量差的标准评估Novalis和扫描计划剂量平面之间的差异。锥形尺寸≤12.5mm的三种情况的平均通过的速率> 85%。虽然总监测单元(MU)以逆方形的方式增加较小的锥形尺寸,但混合扫描方法大大降低了总亩,同时保持与具有Novalis计划的剂量分布。杂交扫描的估计处理时间为12.5mm锥形尺寸平均比顺序计划的22%短。该技术将在允许具有常规圆锥的克星以实现优异的治疗时间来实现优异的剂量分布。

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