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Development of system using beams eye view images to measure respiratory motion tracking errors in image‐guided robotic radiosurgery system

机译:在图像引导的机器人放射外科系统中使用光束的眼图图像测量呼吸运动跟踪误差的系统的开发

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摘要

The accuracy of the CyberKnife Synchrony Respiratory Tracking System (SRTS) is considered to be patient‐dependent because the SRTS relies on an individual correlation between the internal tumor position (ITP) and the external marker position (EMP), as well as a prediction method to compensate for the delay incurred to adjust the position of the linear accelerator (linac). We aimed to develop a system for obtaining pretreatment statistical measurements of the SRTS tracking error by using beam's eye view (BEV) images, to enable the prediction of the patient‐specific accuracy. The respiratory motion data for the ITP and the EMP were derived from cine MR images obtained from 23 patients. The dynamic motion phantom was used to reproduce both the ITP and EMP motions. The CyberKnife was subsequently operated with the SRTS, with a CCD camera mounted on the head of the linac. BEV images from the CCD camera were recorded during the tracking of a ball target by the linac. The tracking error was measured at 15 Hz using in‐house software. To assess the precision of the position detection using an MR image, the positions of test tubes (determined from MR images) were compared with their actual positions. To assess the precision of the position detection of the ball, ball positions measured from BEV images were compared with values measured using a Vernier caliper. The SRTS accuracy was evaluated by determining the tracking error that could be identified with a probability of more than 95% (Ep95). The detection precision of the tumor position (determined from cine MR images) was <0.2mm. The detection precision of the tracking error when using the BEV images was <0.2mm. These two detection precisions were derived from our measurement system and were not obtained from the SRTS. The median of Ep95 was found to be 1.5 (range, 1.0–3.5) mm. The difference between the minimum and maximum Ep95 was 2.5 mm, indicating that this provides a better means of evaluating patient‐specific SRTS accuracy. A suitable margin, based on the predicted patient‐specific SRTS accuracy, can be added to the clinical target volume.PACS number: 87.53.Ly
机译:电子刀同步呼吸追踪系统(SRTS)的准确性被认为是取决于患者的,因为SRTS依赖于内部肿瘤位置(ITP)与外部标志物位置(EMP)之间的个体相关性以及一种预测方法补偿为调整线性加速器(直线加速器)的位置而引起的延迟。我们旨在开发一种系统,用于通过使用光束的眼图(BEV)图像获得SRTS跟踪误差的预处理统计测量值,从而能够预测特定于患者的准确性。 ITP和EMP的呼吸运动数据来自23位患者的电影MR图像。动态运动体模用于再现ITP和EMP运动。赛博刀随后通过SRTS进行操作,并在直线加速器头部安装了CCD摄像机。直线加速器跟踪球目标期间,记录了来自CCD摄像机的BEV图像。使用内部软件在15 Hz下测量跟踪误差。为了评估使用MR图像进行位置检测的精度,将试管的位置(由MR图像确定)与实际位置进行了比较。为了评估球位置检测的精度,将从BEV图像测量的球位置与使用游标卡尺测量的值进行比较。通过确定可以以超过95%的概率(Ep95)识别的跟踪误差来评估SRTS准确性。肿瘤位置的检测精度(由电影MR图像确定)为 / mo> 0.2 mm 。使用BEV图像时跟踪错误的检测精度为 / mo> 0.2 mm 。这两个检测精度来自我们的测量系统,而不是来自SRTS。发现Ep95的中位数为1.5(范围:1.0-3.5)mm。最小和最大Ep95之差为2.5 mm,表明这为评估患者特定的SRTS准确性提供了更好的方法。根据预测的患者特异性SRTS准确性,可以在临床目标体积中增加合适的余量PACS编号:87.53。

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