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Combination of vasculature targeting hypofractionated radiotherapy and immune checkpoint inhibitor elicits potent antitumor immune response and blocks tumor progression

机译：血管系统靶向低次辐射放射治疗和免疫检查点抑制剂引发有效的抗肿瘤免疫应答并阻断肿瘤进展

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期刊名称 Journal for Immunotherapy of Cancer
作者
Stefano Pierini; Abhishek Mishra; Renzo Perales-Linares; Mireia Uribe-Herranz; Silvia Beghi; Andrea Giglio; Sergei Pustylnikov; Francesca Costabile; Stavros Rafail; Augusto Amici; John G Facciponte; Costantinos Koumenis; Andrea Facciabene;
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作者单位

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年(卷),期 2021(9),2
年度 2021
页码 e001636
总页数 17
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
radiotherapy; immunotherapy; vaccination;

机译：放射疗法;免疫疗法;疫苗接种;

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专利

1. Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma [J] . Alessandra Lopes, Kevin Vanvarenberg, ?pela Kos, Scientific reports. . 2018,第1期

机译：免疫检查点封锁与DNA癌症疫苗的结合可诱导针对P815肥大细胞瘤的有效抗肿瘤免疫
2. Immune Checkpoint Blockade Mediated by a Small-Molecule Nanoinhibitor Targeting the PD-1/PD-L1 Pathway Synergizes with Photodynamic Therapy to Elicit Antitumor Immunity and Antimetastatic Effects on Breast Cancer [J] . Rui Zhang, Zhiyan Zhu, Hongying Lv, Small . 2019,第49期

机译：由小分子纳米烟穴介导的免疫检查点延迟靶向PD-1 / PD-L1途径的促进促进光动力疗法，以引发抗肿瘤免疫和对乳腺癌的抗致抗体作用
3. Targeting Tumor Vasculature with TNF Leads Effector T Cells to the Tumor and Enhances Therapeutic Efficacy of Immune Checkpoint Blockers in Combination with Adoptive Cell Therapy [J] . Elia Angela Rita, Grioni Matteo, Basso Veronica, Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第9期

机译：用TNF引导肿瘤脉管系统导致肿瘤效应T细胞，并增强免疫检查点阻断剂的治疗功效与养殖细胞疗法组合
4. AT1412: A Patient-Derived Antibody Targeting the Tetraspanin CD9 Inhibits Tumor Progression by Stimulating the Influx of Immune Cells [C] . Koen Wagner, Remko Schotte, Els Verdegaal, Protein Engineering Summit. . 2018

机译：AT1412：靶向Tetraspanin CD9的患者衍生的抗体通过刺激免疫细胞的膨胀来抑制肿瘤进展
5. Understanding How Adrenergic Stress Signaling Impacts the Anti-Tumor Immune Response and the Efficacy of Checkpoint Inhibitors in Murine Tumor Models [D] . Bucsek, Mark Joseph. 2019

机译：了解肾上腺素能应激信号如何影响抗肿瘤免疫应答以及检查点抑制剂在鼠肿瘤模型中的疗效
6. Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma [O] . Alessandra Lopes, Kevin Vanvarenberg, Špela Kos, -1

机译：免疫检查点封锁与DNA癌症疫苗的结合可诱导针对P815肥大细胞瘤的有效抗肿瘤免疫
7. In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis [O] . Seohyun Kim, Seong A Kim, Gi-Hoon Nam, 2021

机译：通过光动力疗法和Rho-激酶抑制的组合诱导的原位免疫原性清除敏感免疫检查点阻断反应，以引发抗人工心肌瘤及其转移的全身抗肿瘤免疫力
8. Dendritic Cells Transduced with a Wild-Type Self Gene Elicit Potent Antitumor Immune Responses. [R] . Gabrilovich, D., Carbone, D., Chada, S., 2005

机译：用野生型自身基因转导的树突状细胞引发有效的抗肿瘤免疫应答。

Combination of vasculature targeting hypofractionated radiotherapy and immune checkpoint inhibitor elicits potent antitumor immune response and blocks tumor progression

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