Is Gastroesophageal Reflux Disease Really a Risk Factor for Acute Myocardial Infarction?

摘要

Acute myocardial infarction (AMI) is an often-fatal disease. Well-known risk factors of AMI include diabetes mellitus, hypertension, hypercholesterolemia, smoking, alcohol consumption, and obesity.1 Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder, and is associated with esophageal acid exposure. Over the last several decades, studies have shown that GERD exacerbates myocardial ischemia and reduces coronary blood flow,2,3 but no clear conclusions have been made on the association between GERD and AMI in actual practice.