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Clinical and biochemical factors associated with acute myocardial infarction: Risk factors for acute myocardial infarction

机译:与急性心肌梗死相关的临床和生化因素:急性心肌梗死的危险因素

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Because acute myocardial infarction (ami) frequently occurs suddenly without any preceding clinical symptoms, the prediction of ami is clinically of great importance. the principal element of the pathogenesis of ami is the rupture of coronary atherosclerotic plaques rather than gradual progression of atherosclerosis to complete occlusion. Identification of factors concerned with plaque rupture should therefore enable to predict the risk of AMI. Two hundred AMI patients compared to 250 healthy controls. Higher diastolic blood pressure (DBP), systolic blood pressure (SBP), triglyceride, total cholesterol, LDL-cholesterol, HDL-cholesterol and fasting glucose were also shown in AMI patients group. In logistic regression analysis, smoking, hypertension (HTA) and diabetes were significant independent predictors of AMI. The patients with 1VD with multi-vessel disease with stenoses in one coronary vessels were the most frequent (33.3%), and approximately 90% of patients had a critical arterial occlusion (>90%) in coronary vessels. Due to our limited sample size our findings require confirmation in larger cohortes.
机译:由于急性心肌梗塞(ami)经常突然发作而没有任何先前的临床症状,因此对ami的预测在临床上非常重要。 AMI发病机理的主要因素是冠状动脉粥样硬化斑块的破裂,而不是逐渐发展成完全闭塞的动脉粥样硬化。因此,与斑块破裂有关的因素的识别应该能够预测AMI的风险。 200名AMI患者与250名健康对照组相比。 AMI患者组也显示较高的舒张压(DBP),收缩压(SBP),甘油三酸酯,总胆固醇,LDL-胆固醇,HDL-胆固醇和空腹血糖。在逻辑回归分析中,吸烟,高血压(HTA)和糖尿病是AMI的重要独立预测因子。在一个冠状动脉中患有多血管疾病且有狭窄的1VD患者最为频繁(33.3%),约90%的患者冠状动脉有严重动脉闭塞(> 90%)。由于我们的样本量有限,我们的研究结果需要在较大的队列中进行确认。

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