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Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways

机译：肺和肝肿瘤微环境转移胰腺癌的多环境分析显示出特异性特异性免疫调节途径

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The online version contains supplementary material available at 10.1186/s13059-021-02363-6.

机译：在线版本包含10.1186 / S13059-021-02363-6的补充材料。

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期刊名称 Genome Biology
作者
Won Jin Ho; Rossin Erbe; Ludmila Danilova; Zaw Phyo; Emma Bigelow; Genevieve Stein-O’Brien; Dwayne L. Thomas II; Soren Charmsaz; Nicole Gross; Skylar Woolman; Kayla Cruz; Rebecca M. Munday; Neeha Zaidi; Todd D. Armstrong; Marcelo B. Sztein; Mark Yarchoan; Elizabeth D. Thompson; Elizabeth M. Jaffee; Elana J. Fertig;
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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 23
原文格式 PDF
正文语种
中图分类生物学;
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专利

1. Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer [J] . Xiao Yi, Ma Ding, Zhao Shen, Clinical cancer research: an official journal of the American Association for Cancer Research . 2019,第16期

机译：多OMICS分析显示了不同的微环境表征，并表明了三阴性乳腺癌的免疫逃逸机制
2. MiR-142 modulates human pancreatic cancer proliferation and invasion by targeting hypoxia-inducible factor 1 (HIF-1???±) in the tumor microenvironments MiR-142 modulates human pancreatic cancer proliferation and invasion by targeting hypoxia-inducible factor 1 (HIF-1???±) in the tumor microenvironments MiR-142 modulates human pancreatic cancer proliferation and invasion by targeting hypoxia-inducible factor 1 (HIF-1???±) in the tumor microenvironments [J] . Xuejun Gong, Yebin Lu, Wei Wei, Biology Open . 2017,第2期

机译：MiR-142通过在肿瘤微环境中靶向缺氧诱导因子1（HIF-1 ???±）来调节人胰腺癌的增殖和侵袭MiR-142通过靶向低氧诱导因子1（HIF-在肿瘤微环境中的1 ???±）MiR-142通过在肿瘤微环境中靶向缺氧诱导因子1（HIF-1 ???±）来调节人胰腺癌的增殖和侵袭。
3. Remodeling tumor immune microenvironment via targeted blockade of PI3K-gamma and CSF-1/CSF-1R pathways in tumor associated macrophages for pancreatic cancer therapy [J] . Journal of Controlled Release: Official Journal of the Controlled Release Society . 2020,第期

机译：通过靶向阻断肿瘤免疫细胞对肿瘤相关巨噬细胞的PI3K-GAMMA和CSF-1 / CSF-1R途径进行重塑肿瘤免疫微环境进行胰腺癌治疗
4. Gamma Knife Surgery for Metastatic Brain Tumors from Lung Cancer without Prophylactic Whole Brain Radiation Therapy [C] . Torn Serizawa, Yoshinori Higuchi, Junichi Ono, International Stereotactic Radiosurgery Society . 2006

机译：没有预防性全脑放射治疗的肺癌转移性脑肿瘤的伽玛刀手术
5. Blocking immunosuppressive factors and taking advantage of the nutrient supply within the tumor microenvironment: Pathways to achieve improved cancer immunotherapeutic efficacy for patients with metastatic melanoma [D] . Zhang, Ying. 2016

机译：阻断免疫抑制因子并利用肿瘤微环境内的营养供应：途径，以实现转移性黑素瘤患者的改善癌症免疫治疗疗效
6. Multi-Omics Perspective Reveals the Different Patterns of Tumor Immune Microenvironment Based on Programmed Death Ligand 1 (PD-L1) Expression and Predictor of Responses to Immune Checkpoint Blockade across Pan-Cancer [O] . Kaitang Huang, Meiling Hu, Jiayun Chen, 2021

机译：多OMICS透视揭示基于编程死亡配体1（PD-L1）的肿瘤免疫微环境的不同模式表达和预测对泛癌症的免疫检查点阻断的反应
7. Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer [O] . Yi Xiao, Ding Ma, Shen Zhao, 2019

机译：多OMICS分析显示了不同的微环境表征，并表明了三阴性乳腺癌的免疫逃逸机制

Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways

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