Curcumin attenuates angiotensin II‐induced podocyte injury and apoptosis by inhibiting endoplasmic reticulum stress

摘要

Here, we show that curcumin, an active hydrophobic polyphenolic compound extracted from turmeric, could reverse angiotensin II‐induced podocyte injury and apoptosis in a dose‐dependent manner. We found this protective effect of curcumin to be at least partly achieved by inhibiting endoplasmic reticulum stress. Therefore, curcumin may have potential for future development into a possible treatment for chronic kidney disease.