4CPS-050 Comparative study between three sequential semesters to evaluate the implementation of antibiotics’ stewardship programme in intensive care unit of a 500-bed general hospital

摘要

Dissemination of drug-resistant strains is very common in intensive care units (ICU), resulting in combining several antibiotics for prolonged periods. Greece is considered endemic for multi-drug resistant Gram-negative pathogens. An Antibiotics’ Stewardship Programme (ASP), with chief hospital pharmacists to coordinate the stewardship multidisciplinary team, according to national legislation, was activated in March 2017 in our hospital for all clinical departments to initially rationalise the use of crucial protected antibiotics (PA): carbapenems, collistin, tigecycline, linezolid and daptomycin.