LncRNA CBR3-AS1 potentiates Wnt/β-catenin signaling to regulate lung adenocarcinoma cells proliferation migration and invasion

摘要

LncRNA CBR3-AS1 is highly-expressed in LAD and cell lines. a qRT-PCR analysis the expression of lncRNA CBR3-AS1in LAD, LCC or LSCC patient tissues compared with its adjacent non-cancerous tissues. LAD: n = 60; LCC: n = 40; LSCC: n = 40. **P < 0.01, #P > 0.05, one-way analysis of variance (ANOVA). b LAD patients with lncRNA CBR3-AS1 high-expression have shorter overall survival compared to patients with lncRNA CBR3-AS1 low-expression. n = 75, **P < 0.01, two-way ANOVA. c Levels of lncRNA CBR3-AS1 are elevated in LAD cell lines compared with human bronchial epithelial cell line. 0.01 < *P < 0.05, **P < 0.01, one-way ANOVA