Memantine Donepezil or Combination Therapy—What is the best therapy for Alzheimer’s Disease? A Network Meta‐Analysis

摘要

Alzheimer's disease (AD) is a degenerative brain disease that progresses over time, heavily burdening patients, families, and aging societies worldwide. Memantine and donepezil are frequently used in its treatment, both as monotherapy and in combination. This multiple treatment comparison meta‐analysis assessed the efficacy of these regimens and placebo in the management of AD.