首页> 美国卫生研究院文献>BMC Cancer >Correction to: Tumor vasculature-targeted 10B delivery by an Annexin A1-binding peptide boosts effects of boron neutron capture therapy
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Correction to: Tumor vasculature-targeted 10B delivery by an Annexin A1-binding peptide boosts effects of boron neutron capture therapy

机译:校正至:肿瘤脉管系统靶向的10B通过膜蛋白A1结合肽递送促进硼中子捕获治疗的影响

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摘要

Antitumor effect of BNCT in murine MBT2 tumor-bearing mice. a-f Tumor growth curves from the following treatment groups: (a) untreated control (cold control, blue dashed line); (b) IF7C(10BPA)RR injection (cold IF7C(10BPA)RR, red dashed line); (c) IF7K(10BSH)RR injection (cold IF7K(10BSH)RR, black dashed line); (d) Neutron-irradiation (hot control, blue solid line); (e) IF7C(10BPA)RR-mediated BNCT (hot IF7C(10BPA)RR, red solid line); and (f) IF7K(10BSH)RR-mediated BNCT (hot IF7K(10BSH)RR, black solid line). Groups were intravenously injected, and tumors irradiated with epi/thermal neutrons 40 min after injection on day 1. g Tumor growth curve comparing groups analyzed in A-F. Results are expressed as means ± SD. *P < 0.05 (Holm–Sidak method). N.S.: no significant difference. h Body weight of indicated groups. Results are expressed as means ± SD. i Tumor weight of indicated groups at sacrifice. Results are expressed as violin plots with dot plots. Red bold lines indicate the median value, while red dashed lines indicate the interquartile range value (Mann–Whitney test) (j) Photograph of resected tumors from the injected right thighs. If a tumor completely shrank, whole right thighs were resected and labeled as “no tumor”
机译:BNCT在鼠MBT2肿瘤小鼠中的抗肿瘤作用。 A-F肿瘤生长曲线来自以下治疗组:(a)未处理的对照(冷控制,蓝色虚线); (b)IF7C(10BPA)RR注射(冷IF7C(10BPA)RR,红色虚线); (c)IF7K(10BSH)RR注射(冷IF7K(10BSH)RR,黑色虚线); (d)中子辐射(热控制,蓝色实线); (e)IF7C(10BPA)RR介导的BNCT(Hot IF7C(10BPA)RR,红色固体线); (f)IF7K(10BSH)RR介导的BNCT(Hot IF7K(10BSH)RR,黑色实线)。静脉内注射群,并在第1天注射后40分钟用EPI /热中子照射肿瘤。肿瘤生长曲线比较A-F中分析的基团。结果表示为平均值±SD。 * P <0.05(HOLM-SIDAK方法)。 N.S .:没有显着差异。 H表明群体的体重。结果表示为平均值±SD。我牺牲的表明群体的肿瘤重量。结果表示为具有点图的小提琴图。红色粗线表示中值值,而红色虚线表示从注入的右大腿的切除肿瘤的胎面范围值(Mann-Whitney测试)(J)照片。如果肿瘤完全萎缩,整个右大腿被切除并标记为“不肿瘤”

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