Coagulation profile in severe COVID-19 patients: what do we know so far?

摘要

Severe coronavirus disease 2019 (COVID-19) patients may present with single organ failure, but some of them progress to more systemic and multiple organ dysfunctions. One of the most significant markers of poor prognosis in those patients is the development of coagulopathy. These critically ill patients may have abnormal coagulation parameters, which may lead to hypercoagulability and increase the risk of thromboembolic events. Also, severe COVID-19 patients have been associated with disseminated intravascular coagulation (DIC) and increased risk of death.