首页> 美国卫生研究院文献>Neuro-oncology Advances >NQPC-09 PROGNOSIS AND DELAYED COMPLICATIONS OF MEDULLOBLASTOMA IN KOBE CHILDREN’S HOSPITAL
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NQPC-09 PROGNOSIS AND DELAYED COMPLICATIONS OF MEDULLOBLASTOMA IN KOBE CHILDREN’S HOSPITAL

机译:NQPC-09神户儿童医院髓母细胞瘤的预后和延迟并发症

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摘要

Medulloblastoma is the most common pediatric malignant tumor and about 84.2% of cases are under 15 years old. With a current combined-modality approach that includes surgical approach, chemotherapy and radiation therapy, 5 year-survival rates have become 70–85% and also the so-called long-term survivors have increased in our country. This report reviews the prognosis and delayed complications of medulloblastoma in our institute. Cases were 14 boys and 11 girls from January,2010 to May 2019. Mean age was 6.1 years old (4 months to 14 years old). 18 cases receiver gross total removal and 12 cases were high risk group. Exclude recent 4 cases, 15 cases have indicated complete reaction though 6 cases had relapsed or new tumor. The results are that 5 year-survival rates in our institute is 86.7%, but 4 cases had neuro-psychological complications. 5 cases suffered from endocrinal disorders which were not confirmed after the end of all treatments. 2 secondary cancer had appeared 5 and 8 years after the first treatments. The more the survivor in medulloblastoma cases increase, neurosurgeons have to consider long term follow up more than 5 years and pay more attention to support activity of daily life of these patients.
机译:髓母细胞瘤是最常见的小儿恶性肿瘤,约84.2%的病例在15岁以下。目前,包括外科手术,化学疗法和放射疗法在内的综合治疗方法使5年生存率达到70-85%,所谓的长期幸存者在我国也有所增加。本报告回顾了我院髓母细胞瘤的预后和延迟并发症。从2010年1月至2019年5月,病例为14名男孩和11名女孩。平均年龄为6.1岁(4个月至14岁)。接收者总去除量18例,高危组12例。除最近的4例外,尽管有6例复发或有新肿瘤,但仍有15例显示完全反应。结果表明,我院5年生存率为86.7%,但有4例神经心理并发症。所有治疗结束后仍未确认有5例患有内分泌失调。首次治疗后5年和8年出现了2次继发性癌症。髓母细胞瘤病例中幸存者增加的越多,神经外科医生就必须考虑对5年以上的长期随访,并更多地关注这些患者的日常生活活动。

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