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Randomized Phase II Trial of Cisplatin and Etoposide in Combination With Veliparib or Placebo for Extensive-Stage Small-Cell Lung Cancer: ECOG-ACRIN 2511 Study

机译：顺铂和依托泊苷与维利帕利或安慰剂联合用于广泛期小细胞肺癌的随机II期临床试验：ECOG-ACRIN 2511研究

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Veliparib, a poly (ADP ribose) polymerase inhibitor, potentiated standard chemotherapy against small-cell lung cancer (SCLC) in preclinical studies. We evaluated the combination of veliparib with cisplatin and etoposide (CE; CE+V) doublet in untreated, extensive-stage SCLC (ES-SCLC).

机译：在临床前研究中，聚（ADP核糖）聚合酶抑制剂Veliparib增强了针对小细胞肺癌（SCLC）的标准化学疗法。我们在未经治疗的广泛阶段SCLC（ES-SCLC）中评估了维利巴利与顺铂和依托泊苷（CE; CE + V）的组合。

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期刊名称 Journal of Clinical Oncology
作者
Taofeek K. Owonikoko; Suzanne E. Dahlberg; Gabriel L. Sica; Lynne I. Wagner; James L. Wade; III; Gordan Srkalovic; Bradley W. Lash; Joseph W. Leach; Ticiana B. Leal; Charu Aggarwal; Suresh S. Ramalingam;
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年(卷),期 -1(37),3
年度 -1
页码 -1
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学;
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1. Randomized Phase II Trial of Cisplatin and Etoposide in Combination With Veliparib or Placebo for Extensive-Stage Small-Cell Lung Cancer: ECOG-ACRIN 2511 Study [J] . Owonikoko Taofeek K., Dahlberg Suzanne E., Sica Gabriel L., Journal of Clinical Oncology . 2019,第3期

机译：顺铂和依托泊苷的随机期II试验与Veliparib或安慰剂的广泛阶段小细胞肺癌组合：ECOG-acrin 2511研究
2. A phase 1 safety study of veliparib combined with cisplatin and etoposide in extensive stage small cell lung cancer: A trial of the ECOG-ACRIN Cancer Research Group (E2511) [J] . Owonikoko Taofeek K., Dahlberg Suzanne E., Khan Saad A., Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2015,第1期

机译：veliparib联合顺铂和依托泊苷治疗广泛期小细胞肺癌的1期安全性研究：ECOG-ACRIN癌症研究小组（E2511）的试验
3. Patient‐reported tolerability of veliparib combined with cisplatin and etoposide for treatment of extensive stage small cell lung cancer: Neurotoxicity and adherence data from the ECOG ACRIN cancer research group E2511 phase II randomized trial [J] . Laurie E. Steffen McLouth, Fengmin Zhao, Taofeek K. Owonikoko, Cancer Medicine . 2020,第20期

机译：VELIPARIB的患者报告的可耐受性与顺铂和依托泊苷用于治疗广泛阶段的小细胞肺癌：来自ECOG丙烯癌研究组E2511 I2511期随机试验的神经毒性和粘附数据
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
6. A phase 1 safety study of veliparib combined with cisplatin and etoposide in extensive stage small cell lung cancer: A trial of the ECOG-ACRIN Cancer Research Group (E2511) [O] . Taofeek K. Owonikoko, Suzanne E. Dahlberg, Saad A. Khan, -1

机译：veliparib联合顺铂和依托泊苷治疗广泛期小细胞肺癌的1期安全性研究：ECOG-ACRIN癌症研究小组（E2511）的一项试验
7. A phase 1 safety study of veliparib combined with cisplatin and etoposide in extensive stage small cell lung cancer: A trial of the ECOG–ACRIN Cancer Research Group (E2511) [O] . Taofeek K. Owonikoko, Suzanne E. Dahlberg, Saad A. Khan, 2015

机译：Veliparib的第1阶段安全性研究在广泛的阶段小细胞肺癌中与顺铂和依托磷脂结合：E222511的Ecog-acrin癌症研究组试验

Randomized Phase II Trial of Cisplatin and Etoposide in Combination With Veliparib or Placebo for Extensive-Stage Small-Cell Lung Cancer: ECOG-ACRIN 2511 Study

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