Genome-wide study of immune biomarkers in cerebrospinal fluid and serum from patients with bipolar disorder and controls

摘要

For each of the six biomarkers, a Manhattan plot shows the −log10 -value (vertical axis) for all SNPs that pass the standard quality control filters, have a minor allele frequency > 1% and imputation info score > 0.6 along with the chromosome position (horizontal axis). Chromosomes are shown in alternating colors for clarity. The red lines denote genome-wide significant -values −8 while the blue lines show suggestive associations with -values −5.