T14. FUNCTIONAL AND STRUCTURAL CONNECTIVITY IN SUBJECTS AT HIGH RISK FOR PSYCHOSIS AS A POSSIBLE BIOMARKER FOR THEIR TRANSITION TO SCHIZOPHRENIA – A COMBINED EEG AND DTI STUDY

摘要

Altered gamma-band connectivity has been shown across all stages of schizophrenia (SZ) and for persons at High Risk for Psychosis (HRP). Oscillations in the gamma-band frequency range are suggested to play a crucial role for both local and long-range synchronization within the brain during perceptual and cognitive processes. Structural connectivity in the brain is provided by white matter (WM) tracts connecting these areas. Reduced WM integrity is also a feature of SZ that has often been described.