O10.8. STRIATAL CONNECTIVITY IN BREAKTHROUGH PSYCHOSIS ON ANTIPSYCHOTIC MAINTENANCE: PRELIMINARY RESULTS FROM THE BAMM STUDY

摘要

Although antipsychotic drugs are highly efficacious in preventing psychosis relapse, (1) approximately 15% of treatment adherent patients relapse during the maintenance phase. (2) This phenomenon is known as “breakthrough psychosis on antipsychotic maintenance medication” (BAMM). (3) The biological mechanisms of psychotic relapse in treatment adherent individuals are poorly understood.