Translating Chagasic dilating cardiomyopathy to surgical therapies:An under published global challenge

摘要

Chagas disease is a neglected parasitic anthropozoonosis of the Americas linkedto social deprivation with no hope of eradication in the future. Having been themost common non-ischemic cause of dilating cardiomyopathy in Latin America, itnow spreads beyond the geographical boundaries of its vector via imported andautochthonous transmission. We review the evidence on surgery in Chagasic heartfailure and offer a brief narrative on the main aspects of translationalmanagement. There is very limited literature on surgery for Chagasic heartfailure, especially assist devices and transplantation. This may be attributedto the often unsurmountable economic burden of this single-systemparasymphatholytic heart failure to young sufferers who commonly have verylimited access to the aforementioned procedures. Chagasic heart failure offers aso far neglected translational model of parasymphatholytic non-ischemic cardiacfailure.