Accurate diagnosis of lymphoma on whole-slide histopathology images using deep learning

摘要

The distinction between reactive hyperplastic germinal centres ( ) and FL ( ) can be difficult on haematoxylin and eosin (H&E)-stained slides making immunohistochemical stains mandatory for FL diagnosis: Bcl2 expression is down-regulated within reactive germinal centres ( ) while it is expressed in the neoplastic cells in most FL cases ( ).