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RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer

机译：RCC2与小GTPase RalA相互作用并调节胃癌的细胞增殖和运动。

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摘要

Regulator of chromosome condensation 2 (RCC2), also known as TD-60, is associated with various human malignant cancers. RCC2 has been shown to exhibit guanine exchange factor (GEF) activity and contribute to early mitosis. However, the role and mechanism of RCC2 in gastric cancer remain unclear.

机译：染色体浓缩2（RCC2）的调节剂，也称为TD-60，与各种人类恶性肿瘤有关。 RCC2已显示出鸟嘌呤交换因子（GEF）活性并有助于早期有丝分裂。然而，RCC2在胃癌中的作用和机制尚不清楚。

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期刊名称 OncoTargets and therapy
作者
Pengpeng Wang; Wang Zhang; Lili Wang; Wenquan Liang; Aizhen Cai; Yunhe Gao; Lin Chen;
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作者单位

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年(卷),期 2020(13),-1
年度 2020
页码 -1
总页数 11
原文格式 PDF
正文语种
中图分类应用微生物学;肿瘤学;
关键词
RCC2; RalA; gastric cancer; proliferation; migration and invasion;

机译：RCC2;RalA;胃癌;增殖;迁移和侵袭;

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专利

1. RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer [J] . Pengpeng Wang, Wang Zhang, Lili Wang, OncoTargets and therapy . 2020,第2期

机译：RCC2与小GTPAseRAL相互作用，并调节胃癌中细胞增殖和运动
2. MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2 [J] . Mitsuhiro Matsuo, Chisato Nakada, Yoshiyuki Tsukamoto, Molecular Cancer . 2013,第1期

机译：MiR-29c在胃癌中下调并通过靶向RCC2调节细胞增殖
3. STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells [J] . Wei Z., Jiang X., Qiao H., Cellular Signalling . 2013,第4期

机译：STAT3与Skp2 / p27 / p21途径相互作用以调节胃癌细胞的活力和侵袭
4. hERGl Channels Are Overexpressed in Human Gastric Cancer and Their Activity Regulates Cell Proliferation: A Novel Prognostic and Therapeutic Target? [C] . E Lastraioli, F. Gasperi Campani, A. Taddei, International Gastric Cancer Congress . 2005

机译：Hergl频道在人胃癌中过表达，其活性调节细胞增殖：一种新的预后和治疗靶标？
5. Rho GTPases regulate prostate cancer cell proliferation. [D] . Krajewski, Selena Knight. 2003

机译：Rho GTPases调节前列腺癌细胞的增殖。
6. MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2 [O] . Mitsuhiro Matsuo, Chisato Nakada, Yoshiyuki Tsukamoto, 2013

机译：MiR-29c在胃癌中下调并通过靶向RCC2调节细胞增殖
7. MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2 [O] . 2013

机译：MiR-29c在胃癌中下调并通过靶向RCC2调节细胞增殖

RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer

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