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Prevalence of NRAS Mutation PD‐L1 Expression and Amplification and Overall Survival Analysis in 36 Primary Vaginal Melanomas

机译：36例原发性黑色素瘤的NRAS突变发生率PD-L1表达和扩增以及总体生存率分析

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摘要

Primary vaginal melanomas are uncommon and aggressive tumors with poor prognosis, and the development of new targeted therapies is essential. This study aimed to identify the molecular markers occurring in these patients and potentially improve treatment strategies.

机译：原发性阴道黑色素瘤是罕见的侵袭性肿瘤，预后较差，因此开发新的靶向疗法至关重要。这项研究旨在确定这些患者中发生的分子标记，并可能改善治疗策略。

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期刊名称 The Oncologist
作者
Hai‐Yun Wang; Xiao‐Yan Wu; Xiao Zhang; Xin‐Hua Yang; Ya‐Kang Long; Yan‐Fen Feng; Fang Wang;
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作者单位

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年(卷),期 2020(25),2
年度 2020
页码 -1
总页数 11
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Primary vaginal melanoma; Ooncogenic mutations; NRAS; PD‐L1 expression;

机译：原发性阴道黑素瘤;致癌性突变;NRAS;PD-L1表达;

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专利

1. Prevalence of NRAS Mutation, PD‐L1 Expression and Amplification, and Overall Survival Analysis in 36 Primary Vaginal Melanomas [J] . Wang Hai‐Yun, Wu Xiao‐Yan, Zhang Xiao, The oncologist . 2020,第2期

机译：NRAS突变的患病率，PD-L1表达和扩增，以及36名初级阴道黑色素瘤中的总存活分析
2. Prevalence of NRAS Mutation, PD-L1 Expression and Amplification, and Overall Survival Analysis in 36 Primary Vaginal Melanomas [J] . Hai-Yun Wang, Xiao-Yan Wu, Xiao Zhang, The oncologist . 2020,第2期

机译：NRAS突变的患病率，PD-L1表达和扩增，以及36名初级阴道黑色素瘤中的总存活分析
3. Oncogene abnormalities in a series of primary melanomas of the sinonasal tract: NRAS mutations and cyclin D1 amplification are more frequent than KIT or BRAF mutations [J] . ChraybiM., AlsamadI.A., Copie-BergmanC., Human Pathology . 2013,第9期

机译：一系列鼻窦原发性黑色素瘤中的癌基因异常：NRAS突变和细胞周期蛋白D1扩增比KIT或BRAF突变更常见
4. Toward precision breast cancer survival prediction utilizing combined whole genome-wide expression and somatic mutation analysis [C] . Yifan Zhang, William Yang, Dan Li, IEEE International Conference on Bioinformatics and Biomedicine . 2017

机译：利用全基因组表达和体细胞突变分析相结合的精确乳腺癌生存预测
5. NRAS and BRAF mutations in primary cutaneous melanoma: A comparison of mutation rates between radial and vertical growth phases in individual tumors. [D] . Greene, Victoria R. 2007

机译：原发性皮肤黑素瘤中的NRAS和BRAF突变：单个肿瘤在径向和垂直生长期之间的突变率比较。
6. Oncogene abnormalities in a series of primary melanomas of the sinonasal tract: NRAS mutations and cyclin D1 amplification are more frequent than KIT or BRAF mutations [O] . Meriem Chraybi, Issam Abd Alsamad, Christiane Copie-Bergman, -1

机译：一系列鼻窦原发性黑色素瘤中的癌基因异常：NRAS突变和cyclin D1扩增比KIT或BRAF突变更常见
7. Prevalence of NRAS Mutation, PD‐L1 Expression and Amplification, and Overall Survival Analysis in 36 Primary Vaginal Melanomas [O] . Hai‐Yun Wang, Xiao‐Yan Wu, Xiao Zhang, 2019

机译：NRAS突变的患病率，PD-L1表达和扩增，以及36个初级阴道黑色素瘤的总存活分析

Prevalence of NRAS Mutation PD‐L1 Expression and Amplification and Overall Survival Analysis in 36 Primary Vaginal Melanomas

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