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Interleukin-28B Polymorphisms and Response of Chronic Hepatitis C Patients from Indonesia to Pegylated Interferon/Ribavirin Treatment

机译：白细胞介素28B基因多态性和印度尼西亚慢性丙型肝炎患者对聚乙二醇化干扰素/利巴韦林治疗的反应。

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摘要

This study demonstrated that Indonesian patients with chronic hepatitis C (mostly ethnic Java people) mostly were infected with hepatitis C virus (HCV) genotype 1; however, they carried mainly the major genotypes of interleukin 28B (IL-28B) single nucleotide polymorphisms (SNPs) (rs12979860 CC, rs11881222 TT, rs8103142 AA, and rs8099917 TT), and they mostly achieved sustained virological responses to pegylated interferon/ribavirin treatment.

机译：这项研究表明，印度尼西亚的慢性丙型肝炎患者（主要是爪哇人）主要感染了丙型肝炎病毒（HCV）基因型1。但是，它们主要携带白细胞介素28B（IL-28B）单核苷酸多态性（SNP）的主要基因型（rs12979860 CC，rs11881222 TT，rs8103142 AA和rs8099917 TT），并且大多对聚乙二醇化干扰素/利巴韦林治疗实现了持续的病毒学应答。

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期刊名称 Journal of Clinical Microbiology
作者
Juniastuti; Bogi P. Wibowo; I D. N. Wibawa; Takako Utsumi; Syifa Mustika; Mochamad Amin; Rury M. Wahyuni; Hendra Kurniawan; Agus Hendrayana; Poernomo B. Setiawan; Laura N. Yamani; Soetjipto; Yoshihiko Yano; Hak Hotta; Yoshitake Hayashi; Maria I. Lusida;
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年(卷),期 2014(52),6
年度 2014
页码 2193–2195
总页数 3
原文格式 PDF
正文语种
中图分类微生物学;
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专利

1. Interleukin-28B Polymorphisms and Response of Chronic Hepatitis C Patients from Indonesia to Pegylated Interferon/Ribavirin Treatment [J] . Juniastuti, Bogi P. Wibowo, I D. N. Wibawa, Journal of Clinical Microbiology . 2014,第6期

机译：白细胞介素28B基因多态性和印度尼西亚的慢性丙型肝炎患者对聚乙二醇化干扰素/利巴韦林治疗的反应。
2. Polymorphisms in interleukin-10 and interleukin-28B genes in Egyptian patients with chronic hepatitis C virus genotype 4 and their effect on the response to pegylated interferon/ribavirin-therapy [J] . ShakerO.G., SadikN.A.H. Journal of gastroenterology and hepatology . 2012,第12期

机译：埃及慢性丙型肝炎病毒基因型4的患者白细胞介素10和白细胞介素28B基因多态性及其对聚乙二醇干扰素/利巴韦林治疗反应的影响
3. Interleukin-28B polymorphisms on the SVR in the treatment of na?ve chronic hepatitis C with pegylated interferon-α plus ribavirin: A meta-analysis [J] . ShiK.-Q., LiuW.-Y., LinX.-F., Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2012,第1期

机译：聚乙二醇干扰素-α联合利巴韦林治疗初治慢性丙型肝炎时SVR上白介素28B基因多态性的荟萃分析
4. Studies of Therapy with Thymosin α 1 in Combination with Pegylated Interferon α2a and Ribavirin in Nonresponder Patients with Chronic Hepatitis C [C] . ROBERTO CAMERINI, ALESSIA CIANCIO, ALFONSO DE ROSA, International Symposiumn on Thymosins in Health and Disease; 20070321-24; Washington,DC(US) . 2007

机译：胸腺素α1联合聚乙二醇化干扰素α2a和利巴韦林治疗慢性丙型肝炎无反应者的研究
5. The meaning of adherence among veterans receiving pegylated interferon and ribavirin antiviral treatment for chronic hepatitis C. [D] . Phillips, Frances Hinshaw. 2011

机译：接受聚乙二醇干扰素和利巴韦林抗病毒治疗的慢性丙型肝炎退伍军人依从性的含义。
6. Impact of IL28B gene polymorphisms rs8099917 and rs12980275 on response to pegylated interferon-α/ribavirin therapy in chronic hepatitis C genotype 4 patients [O] . Mahmoud A Khattab, Hend M Abdelghany, Maggie M Ramzy, 2016

机译：IL28B基因多态性rs8099917和rs12980275对聚乙二醇化干扰素-α/利巴韦林治疗慢性丙型肝炎4基因型患者反应的影响
7. Association of SCARB1 Gene Polymorphisms with Virological Response in Chronic Hepatitis C Patients Receiving Pegylated Interferon plus Ribavirin Therapy [O] . Ching-Sheng Hsu, Shih-Jer Hsu, Wei-Liang Liu, 2016

机译：瘢痕疙瘩多态性与慢性丙型肝炎患者病毒学反应的关联接受聚乙二醇干扰素加里伐素治疗

Interleukin-28B Polymorphisms and Response of Chronic Hepatitis C Patients from Indonesia to Pegylated Interferon/Ribavirin Treatment

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