The EV-TRACK summary add-on: integration of experimental information in databases to ensure comprehensive interpretation of biological knowledge on extracellular vesicles

摘要

Released in multiple body fluids, EVs protect their content from degradation and are increasingly considered for the development of novel clinical applications such as liquid biopsy tests [ – ]. The development of these tests is currently mainly driven by in-depth analysis of the protein and RNA cargo of EVs using omics approaches to identify biomarkers for disease. In addition, researchers aim to delineate EV functions in (patho)physiological conditions by integrating this knowledge on EV cargo [ ].