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Therapy with Oral Directly Acting Agents in Hepatitis C Infection Is Associated with Reduction in Fibrosis and Increase in Hepatic Steatosis on Transient Elastography

机译：口服直接作用剂在丙型肝炎感染中的治疗与瞬时弹性成像上纤维化的减少和肝脂肪变性的增加有关

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摘要

Direct-Acting Antivirals (DAAs) are now the standard of care for management of Chronic Hepatitis C (CHC) infection. The aim of this study was to evaluate change in Liver Stiffness Measurement (LSM) and Controlled Attenuation Parameter (CAP) by transient elastography (FibroScan®) after completion of DAA therapy.

机译：现在，直接作用抗病毒药物（DAA）是管理慢性丙型肝炎（CHC）感染的护理标准。这项研究的目的是评估在完成DAA治疗后通过瞬时弹性成像（FibroScan®）进行的肝硬度测量（LSM）和受控衰减参数（CAP）的变化。

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期刊名称 Journal of Clinical and Experimental Hepatology
作者
Gyanranjan Rout; Baibaswata Nayak; Arpan H. Patel; Deepak Gunjan; Vishwajeet Singh; Saurabh Kedia; Shalimar;
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作者单位

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年(卷),期 2019(9),2
年度 2019
页码 -1
总页数 8
原文格式 PDF
正文语种
中图分类外科学;
关键词
AASLD; American Association for the Study of Liver Diseases; ALT; Alanine Aminotransferase; AST; Aspartate Aminotransferase; BMI; Body Mass Index; CAP; Controlled Attenuation Parameter; CHC; Chronic Hepatitis C; DAAs; Directly-Acting Antivirals; F0-4; METAVIR Fibrosis Stage 0 to 4; HCV; Hepatitis C Virus; HIV; Human Immunodeficiency Virus; IFN; Interferon; IQR; Interquartile Range; LSM; Liver Stiffness Measurement; NAFLD; Non-alcoholic Fatty Liver Disease; SD; Standard Deviation; SVR12; Sustained Viral Response at 12 Weeks; TE; Transient Elastography;

机译：AASLD;美国肝病研究协会;ALT;丙氨酸转氨酶;AST;天冬氨酸转氨酶;体重指数;身体质量指数;CAP;受控衰减参数;CHC;慢性丙型肝炎;DAA;直接作用抗病毒药;F0-4;METAVIR纤维化阶段0至4;HCV;丙型肝炎病毒;HIV;人类免疫缺陷病毒;干扰素;干扰素;IQR;四分位间距;LSM;肝劲度测量;非酒精性脂肪性肝病SD;标准偏差;SVR12;12周持续病毒反应;TE;瞬态弹性成像;

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专利

1. Assessment of hepatic fibrosis regression by transient elastography in patients with chronic Hepatitis B treated with oral antiviral agents [J] . KimJ.K., MaD.W., LeeK.S., Journal of Korean medical science . 2014,第4期

机译：瞬时弹性成像技术评估口服抗病毒药治疗的慢性乙型肝炎患者肝纤维化消退
2. Assessment of Hepatic Fibrosis Regression by Transient Elastography in Patients with Chronic Hepatitis B Treated with Oral Antiviral Agents [J] . Kim Ja Kyung, Ma Dae Won, Lee Kwan Sik, Journal of Korean medical science. . 2014,第4期

机译：瞬时弹性成像技术评估口服抗病毒药治疗慢性乙型肝炎患者肝纤维化的程度
3. P1‐096: Eradication of chronic hepatitis C infection with direct acting antivirals is associated with reduction in fibrosis by Transient Elastography (FibroScan) [J] . Journal of viral hepatitis. . 2018,第S1期

机译：P1-096：消除直接作用抗病毒的慢性丙型肝炎感染与瞬态弹性造影（Fibroscan）的纤维化降低有关
4. Liver fibrosis in chronic hepatitis B-A study of the natural history using transient elastography. [D] . Wong Lai-Hung, Grace. 2010

机译：慢性乙型肝炎的肝纤维化-使用瞬时弹性成像研究自然史。
5. Assessment of Hepatic Fibrosis Regression by Transient Elastography in Patients with Chronic Hepatitis B Treated with Oral Antiviral Agents [O] . Ja Kyung Kim, Dae Won Ma, Kwan Sik Lee, 2014

机译：瞬时弹性成像对口服抗病毒药治疗慢性乙型肝炎患者肝纤维化消退的评估
6. Therapy with Oral Directly Acting Agents in Hepatitis C Infection Is Associated with Reduction in Fibrosis and Increase in Hepatic Steatosis on Transient Elastography [O] . Gyanranjan Rout, Baibaswata Nayak, Arpan H. Patel, 2019

机译：丙型肝炎感染中口服直接作用剂的治疗与近纤维化的降低相关，瞬态弹性显影的肝脏脂肪变性增加有关

Therapy with Oral Directly Acting Agents in Hepatitis C Infection Is Associated with Reduction in Fibrosis and Increase in Hepatic Steatosis on Transient Elastography

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