首页> 美国卫生研究院文献>Journal of Clinical Microbiology >Mucor circinelloides as a Cause of Invasive Maxillofacial Zygomycosis: an Emerging Dimorphic Pathogen with Reduced Susceptibility to Posaconazole
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Mucor circinelloides as a Cause of Invasive Maxillofacial Zygomycosis: an Emerging Dimorphic Pathogen with Reduced Susceptibility to Posaconazole

机译:Mucor circinelloides作为侵袭性颌面部合胞菌病的原因:一种新兴的二态性病原体对泊沙康唑的敏感性降低

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摘要

A case of maxillofacial zygomycosis caused by Mucor circinelloides, identified by phenotypic and molecular methods and treated successfully with liposomal amphotericin B (AmBisome) and surgical debridement, is described. The isolate was resistant to posaconazole. This report underscores the importance of prior susceptibility testing of zygomycetes to guide therapy with the most effective antifungal agent for an improved prognosis.
机译:描述了一例由表型和分子方法鉴定并由脂质体两性霉素B(AmBisome)和外科清创术成功治疗的由Mucor circinelloides引起的颌面部合子病。该分离物对泊沙康唑具有抗性。该报告强调了对合子菌进行药敏试验的重要性,以指导使用最有效的抗真菌剂治疗以改善预后。

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