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Accelerated Cognitive Ageing in epilepsy: exploring the effective connectivity between resting-state networks and its relation to cognitive decline

机译：癫痫的加速认知老化：探索静息状态网络之间的有效联系及其与认知衰退的关系

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摘要

This study aims at understanding the dynamic functional brain organization in Accelerated Cognitive Ageing (ACA) in epilepsy. We also assess to which extend the (abnormal) effective connectivity between brain networks correlates with the (estimated) decline in IQ scores observed in the ACA patients.

机译：这项研究旨在了解癫痫的加速认知老化（ACA）中的动态功能性大脑组织。我们还评估了脑网络之间（异常）有效连接的扩展与在ACA患者中观察到的（估计）智商得分下降（相关）有关。

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期刊名称 Heliyon
作者
A. Bernas; L.E.M. Breuer; R. Lamerichs; A.J.A. de Louw; A.P. Aldenkamp; S. Zinger;
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作者单位

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年(卷),期 2020(6),6
年度 2020
页码 -1
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
Neuroscience; Image processing; Cognitive neuroscience; Cognition; Aging; Nervous system; Psychiatry; Medical imaging; Clinical research; Biomarkers; Mental health; Fmri; Accelerated cognitive ageing; Epilepsy; Ageing; Cognitive decline; Granger causality; Effective connectivity;

机译：神经科学;图像处理;认知神经科学;认知;衰老;神经系统;精神病学;医学成像;临床研究;生物标记物;精神健康;Fmri;加速认知老化;癫痫症;年龄;认知能力下降;格兰杰因果关系;有效连接;

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专利

1. SCENE-ENCODING ACTIVATION AND RESTING-STATE FUNCTIONAL CONNECTIVITY IN OLDER ADULTS WITH SUBJECTIVE COGNITIVE DECLINE AND MILD COGNITIVE IMPAIRMENT [J] . Lauren K. Lynch, Shannon L. Risacher, Brenna C. McDonald, Alzheimer’s & dementia: the journal of the Alzheimer’s Association . 2018,第7期

机译：具有主观认知下降和轻度认知障碍的老年人的场景编码激活和休息状态功能
2. Altered effective connectivity of the default mode network in resting-state amnestic type mild cognitive impairment [J] . YanH., ZhangY., ChenH., Journal of the International Neuropsychological Society: JINS . 2013,第4期

机译：默认模式网络在静息状态记忆删除型轻度认知障碍中的有效连接改变
3. Cognitive deterioration in adult epilepsy: clinical characteristics of "Accelerated Cognitive Ageing" [J] . Breuer L. E. M., Grevers E., Boon P., Acta neurologica Scandinavica. . 2017,第1期

机译：成人癫痫的认知劣化：“加速认知老化”的临床特征
4. Exploring the effective connectivity of resting state networks in Mild Cognitive Impairment: an fMRI study combining ICA and multivariate Granger causality analysis [C] . Zhenyu Liu, Lijun Bai, Ruwei Dai, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2012

机译：探索静息状态网络在轻度认知障碍中的有效连通性：COMRI和多元格兰杰因果区分析结合的FMRI研究
5. Evaluating Default Mode Network Resting-State Functional Connectivity as a Biomarker of Treatment Response to Mindfulness-Based Cognitive Therapy for Anhedonia [D] . Cernasov, Paul Michael. 2020

机译：评估默认模式网络静态功能连接作为对anhedonia的正念的认知治疗的治疗响应的生物标志物
6. Emulative coherent and causal dynamics between large-scale brain networks are neurobiomarkers of Accelerated Cognitive Ageing in epilepsy [O] . Antoine Bernas, Lisanne E. M. Breuer, Albert P. Aldenkamp, 2021

机译：大规模脑网络之间的仿真相干和因果动态是癫痫中加速认知老龄化的神经杀虫剂
7. 4.1 COGNITIVE RESERVE ATTENUATES AGE-RELATED COGNITIVE DECLINE IN THE CONTEXT OF ACCELERATED BRAIN AGEING IN SCHIZOPHRENIA-SPECTRUM DISORDERS: EVIDENCE FOR ACTIVE COMPENSATION [O] . Tamsyn Van Rheenen, Vanessa Cropley, Birgitte Fagerlund, 2019

机译：4.1认知储备在精神分裂症患者中加速脑老化的背景下衰减年龄相关的认知下降：积极赔偿的证据

Accelerated Cognitive Ageing in epilepsy: exploring the effective connectivity between resting-state networks and its relation to cognitive decline

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