Potential therapeutic effects of endothelial cells trans-differentiated from Wharton’s Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model

摘要

Separation and differentiation of WJ-MSCs into ECs. Inverted microscope image of Wharton’s Jelly-derived MSCs showing adherent fibroblasts-like cells (X 100). Inverted microscope image of ECs differentiated from MSCs following VEGF application (X 100, insert X 400). Expression of CD44, CD31 and CD 34 in WJ-MSCs, and expression of CD31 and CD34 10 days after VEGF application. (*Significant (p d Representative flow cytometry analysis of CD44, CD31 and CD 34 in WJ-MSCs before and after VEGF application. (Significant = p •Significant when compared to CD31 expression in WJ-MSCs. Significant when compared to CD34 expression in WJ-MSCs. N = 10)