Assessing Human Molybdenum Nutritional Status by Analyzing Frequency distribution Properties in the Hair and Whole Blood with a Median Derivatives Bioassay

摘要

Molybdenum is the essential trace element in human nutrition since it is a part of a pterin coenzyme which is essential for the activity of various oxidases. High doses of Mo are neurotoxic to the human brain. The safe adequate intake of Mo is set at 75–200 µg·g , but there is no available long-term biological indicator tissue to assess the Mo nutritional status. The aim of this study was to assess human Mo nutritional status with a median derivatives bioassay.