Lycopene Supplementation Either Purified or as in Tomato Powder to the Diet of Laying Hens Lowers Egg Yolk Cholesterol by Modulation of Sterol Transporters

摘要

The objective of this work was to investigate the effects of dietary supplementation of purified lycopene (LYC) or a source of LYC as in tomato powder (TP) on live hen performance, egg yolk cholesterol concentrations as well as the gene expressions related to mechanism and regulation of cholesterol, namely Niemann-Pick C1-like 1 protein (NPC1L1), acyl-CoA: cholesterol acyltransferase 2 (ACAT2), microsomal triacylglycerol transport protein (MTP), ATP binding cassette transporters sub-family G member 5 and 8 (ABCG5/8), ATP citrate lyase (ACLY), liver X receptor alpha (LXRα) and sterol regulatory element-binding proteins (SREBP1c).